EsxB, a secreted protein fromBacillus anthracisforms two distinct helical bundles

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EsxB, a secreted protein from Bacillus anthracis forms two distinct helical bundles

The EsxB protein from Bacillus anthracis belongs to the WXG100 family, a group of proteins secreted by a specialized secretion system. We have determined the crystal structures of recombinant EsxB and discovered that the small protein (∼10 kDa), comprised of a helix-loop-helix (HLH) hairpin, is capable of associating into two different helical bundles. The two basic quaternary assemblies of Esx...

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ژورنال

عنوان ژورنال: Protein Science

سال: 2015

ISSN: 0961-8368

DOI: 10.1002/pro.2715